Scientists at IIT Kanpur have achieved an important breakthrough in understanding the causes of diabetes and exploring a new direction for its treatment. Researchers have found that immune cells present in the pancreas can affect the functioning of insulin-producing beta cells. Certain fat molecules released by these immune cells obstruct insulin secretion. Understanding this process has raised hopes of developing new options for the treatment of type-2 diabetes.
Key role of signals between cells
According to the research, when Gq signaling is activated in immune cells called macrophages present in the pancreas, a process called AMPK is affected. After this, the secretion of fat molecules called sphingolipids increases. These molecules can reduce the activity of insulin-producing beta cells. Scientists have also identified the role of the GPR18 receptor in this process.
Possibility of developing a new drug
Researchers believe that identifying targets that control this biological process could help in developing drugs in the future that may support better insulin secretion. However, this research is still an early scientific basis in the direction of treatment. Extensive further trials will be necessary to develop a new drug and confirm that it is safe and effective.
Hashtags: #UttarPradeshState #Bhopal #IIT #Kanpur #Research #Diabetes #Treatment #Hope #CNN #IITKanpurResearchOn
