CNN Central News & Network–ITDC India Epress/ITDC News Bhopal: In a significant advancement in cardiac care, specialists at Indraprastha Apollo Hospitals successfully performed a complex leadless pacemaker implantation in a 65-year-old patient with a metallic prosthetic tricuspid valve. The procedure, performed by Dr Vanita Arora, marks the first time in India that a leadless pacemaker has been implanted through a metallic prosthetic valve, offering a safer, non-surgical treatment option for patients with similar complex cardiac histories.
The patient had a long and complicated medical journey. He underwent pancreaticojejunostomy (surgical procedure that connects the pancreas to the jejunum (small intestine) to drain pancreatic enzymes), in 1998, after which he developed fungal infective endocarditis affecting the tricuspid valve. In 2000, he required cardiac surgery with debridement of the tricuspid valve. Over time, he developed severe tricuspid regurgitation that led to symptoms of right-sided heart failure. In 2018, his condition required tricuspid valve replacement with a 31 mm metallic bileaflet mechanical prosthesis (Artivion On-X valve).
Recently, the patient developed dizziness and episodes of presyncope. Evaluation revealed symptomatic sinus node dysfunction along with atrioventricular conduction disease, making permanent pacemaker implantation necessary.
However, conventional pacemaker implantation was not feasible because pacing leads cannot safely pass through a mechanical tricuspid valve, as this may damage the prosthesis and increase the risk of valve dysfunction, thrombosis and lead failure. In addition, repeat open-heart surgery to place epicardial leads was considered high risk because the patient had already undergone multiple cardiac procedures.
The cardiac electrophysiology team led by Dr Vanita, therefore opted for a leadless pacing system. Unlike traditional pacemakers that require leads placed through veins into the heart, a leadless pacemaker is a small self-contained device that is delivered directly into the heart through a catheter inserted via a vein in the leg. This approach eliminates the need for leads and avoids interference with the prosthetic valve.
In this case, a dual-chamber Aveir leadless pacemaker capable of maintaining atrioventricular synchrony was implanted. The procedure required careful planning, including detailed mapping of the heart, safe navigation across the mechanical valve and precise fixation of the device within the right ventricle. The successful implantation restored normal heart rhythm while preserving the function of the prosthetic valve.
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